A new cause of limbic encephalopathy

A new cause of limbic encephalopathy.

A new cause of limbic encephalopathy The spectrum of antibody-associated encephalopathy seems ever increasing. In 2004 Vincent et al. described, in this journal, a series of patients with a reversible limbic encephalopathy associated with antibodies against the voltage-gated potassium channels (VGKC-Ab). In this issue, Ances et al. (2005) have described yet another cause of limbic encephalopath...

CDKL5 Encephalopathy: A Rare Cause of Infantile Epileptic Encephalopathy.

Another rare cause of encephalopathy.

To cite: Baibars M, Coker R, Alraiyes AH, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-200928 DESCRIPTION A 45-year-old woman with a medical history of Hashimoto’s thyroiditis presented with a progressively worsening occipital headache for 24 h associated with blurry vision and vomiting. The headache had an intermittent pattern with no pain-free pe...

Multifocal encephalopathy and autoimmune-mediated limbic encephalitis following tocilizumab therapy.

A 63-year-old man with rheumatoid arthritis developed multifocal encephalopathy and limbic encephalitis following therapy with tocilizumab, a humanized anti-interleukin-6 receptor antibody. Anti-glutamate receptor ε2 antibodies were later found to be positive in both the serum and cerebrospinal fluid. This case highlights the possibility of the development of encephalopathy after treatment with...

HCN1 Gain-Of-Function Mutations - A New Cause of Epileptic Encephalopathy.

Commentary Early infantile epileptic encephalopathy (EIEE) refers to severe early onset epilepsy with associated neurodevelopmental abnormalities. The term was used initially to reflect EIEE with suppression-burst pattern on EEG, or Ohtahara syndrome, but it has been applied more widely to a larger and growing group of epileptic encephalopathies; patients with mutations in the EIEE genes displa...